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shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination
Recombination is crucial for chromosome pairing and segregation during meiosis. SPATA22, along with its direct binding partner and functional collaborator, MEIOB, is essential for the proper repair of double-strand breaks (DSBs) during meiotic recombination. Here we describe a novel point-mutated al...
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| Veröffentlicht in: | Chromosoma |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7546082/ https://ncbi.nlm.nih.gov/pubmed/32388826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-020-00735-8 |
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