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shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination

Recombination is crucial for chromosome pairing and segregation during meiosis. SPATA22, along with its direct binding partner and functional collaborator, MEIOB, is essential for the proper repair of double-strand breaks (DSBs) during meiotic recombination. Here we describe a novel point-mutated al...

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Bibliografiske detaljer
Udgivet i:Chromosoma
Main Authors: Petrillo, Cynthia, Barroca, Vilma, Ribeiro, Jonathan, Lailler, Nathalie, Livera, Gabriel, Keeney, Scott, Martini, Emmanuelle, Jain, Devanshi
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546082/
https://ncbi.nlm.nih.gov/pubmed/32388826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-020-00735-8
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