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shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination

Recombination is crucial for chromosome pairing and segregation during meiosis. SPATA22, along with its direct binding partner and functional collaborator, MEIOB, is essential for the proper repair of double-strand breaks (DSBs) during meiotic recombination. Here we describe a novel point-mutated al...

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Bibliografische gegevens
Gepubliceerd in:Chromosoma
Hoofdauteurs: Petrillo, Cynthia, Barroca, Vilma, Ribeiro, Jonathan, Lailler, Nathalie, Livera, Gabriel, Keeney, Scott, Martini, Emmanuelle, Jain, Devanshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546082/
https://ncbi.nlm.nih.gov/pubmed/32388826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-020-00735-8
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