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Mechanism and Regulation of Meiotic Recombination Initiation

Meiotic recombination involves the formation and repair of programmed DNA double-strand breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent studies pertaining to the formation of meiotic DSBs, including the mechanism of DNA cleavage by Spo11, proteins required for b...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Biol
Main Authors: Lam, Isabel, Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292169/
https://ncbi.nlm.nih.gov/pubmed/25324213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016634
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