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Iron Fenton oxidation of 2′-deoxyguanosine in physiological bicarbonate buffer yields products consistent with the reactive oxygen species carbonate radical anion not hydroxyl radical
Product analysis from the iron Fenton oxidation of 2′-deoxyguanosine found reactions in bicarbonate buffer yield 8-oxo-2′-deoxyguanosine and spiroiminodihyantoin consistent with CO(3)(•−). Reactions in phosphate buffer furnished high yields of sugar oxidation products consistent with HO(•). These ob...
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| Veröffentlicht in: | Chem Commun (Camb) |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7545335/ https://ncbi.nlm.nih.gov/pubmed/32716425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc04138f |
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