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Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent?

The ability of oxyhaemoglobin and methaemoglobin to generate hydroxyl radicals (OH.) from H2O2 has been investigated using deoxyribose and phenylalanine as 'detector molecules' for OH.. An excess of H2O2 degrades methaemoglobin, releasing iron ions that react with H2O2 to form a species th...

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Bibliografische gegevens
Hoofdauteurs: Puppo, A, Halliwell, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148683/
https://ncbi.nlm.nih.gov/pubmed/3342006
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