Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Detection of 'free' iron in biological systems by using bleomycin-dependent degradation of DNA.

Bleomycin in the presence of iron(II) degrades DNA to form a thiobarbituric acid-reactive product. This has been made the basis of a specific assay method for 'free' iron in biological fluids. Human synovial fluid, human cerebrospinal fluid and rat pleural-exudate fluid were found to conta...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Gutteridge, J M, Rowley, D A, Halliwell, B
Formato: Artigo
Idioma:Inglês
Publicado: 1981
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163361/
https://ncbi.nlm.nih.gov/pubmed/6175315
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares