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On the Irrelevancy of Hydroxyl Radical to DNA Damage from Oxidative Stress and Implications for Epigenetics

Contrary to frequent reports in the literature, hydroxyl radical is not a key species participating in endogenous oxidative DNA damage. Instead, carbonate radical anion is formed from the Fenton reaction under cellular conditions and from decomposition of nitrosoperoxycarbonate generated during infl...

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Dettagli Bibliografici
Pubblicato in:Chem Soc Rev
Autori principali: Fleming, Aaron M., Burrows, Cynthia J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522918/
https://ncbi.nlm.nih.gov/pubmed/32785348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cs00579g
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