Identification of structurally related antibodies in antibody sequence databases using Rosetta-derived position-specific scoring

The amount of antibody (Ab) variable gene sequence information is expanding rapidly, but our ability to predict the function of Abs from sequence alone is limited. Here, we describe a sequence-to-function prediction method that couples structural data for a single Ab/Antigen (Ag) complex with repert...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Finn, Jessica A., Dong, Jinhui, Sevy, Alexander M., Parrish, Erica, Gilchuk, Iuliia, Nargi, Rachel, Scarlett-Jones, Morgan, Reichard, Walter, Bombardi, Robin, Voss, Thomas G., Meiler, Jens, Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544681/
https://ncbi.nlm.nih.gov/pubmed/32783953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.07.012
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