Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures

BACKGROUND: Advances in next-generation sequencing (NGS) of antibody repertoires have led to an explosion in B cell receptor sequence data from donors with many different disease states. These data have the potential to detect patterns of immune response across populations. However, to this point it...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Bioinformatics
Prif Awduron: Sevy, Alexander M., Soto, Cinque, Bombardi, Robin G., Meiler, Jens, Crowe, James E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Methodology Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894320/
https://ncbi.nlm.nih.gov/pubmed/31801472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3281-8
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