RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival

G protein–coupled receptors are critical mediators of platelet activation whose signaling can be modulated by members of the regulator of G protein signaling (RGS) family. The 2 most abundant RGS proteins in human and mouse platelets are RGS10 and RGS18. While each has been studied individually, cri...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: DeHelian, Daniel, Gupta, Shuchi, Wu, Jie, Thorsheim, Chelsea, Estevez, Brian, Cooper, Matthew, Litts, Kelly, Lee-Sundlov, Melissa M., Hoffmeister, Karin M., Poncz, Mortimer, Ma, Peisong, Brass, Lawrence F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2020
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544544/
https://ncbi.nlm.nih.gov/pubmed/32542378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003251
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky