Modulating platelet reactivity through control of RGS18 availability

Most platelet agonists activate platelets by binding to G-protein–coupled receptors. We have shown previously that a critical node in the G-protein signaling network in platelets is formed by a scaffold protein, spinophilin (SPL), the tyrosine phosphatase, Src homology region 2 domain-containing pho...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Ma, Peisong, Ou, Kristy, Sinnamon, Andrew J., Jiang, Hong, Siderovski, David P., Brass, Lawrence F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671108/
https://ncbi.nlm.nih.gov/pubmed/26407691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-640037
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