Загрузка...
Unbiased investigation of specificities of prime editing systems in human cells
Prime editors (PEs) enable targeted precise editing, including the generation of substitutions, insertions and deletions, in eukaryotic genomes. However, their genome-wide specificity has not been explored. Here, we developed Nickase-based Digenome-seq (nDigenome-seq), an in vitro assay that uses wh...
Сохранить в:
| Опубликовано в: : | Nucleic Acids Res |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2020
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544197/ https://ncbi.nlm.nih.gov/pubmed/32941652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa764 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|