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Divergent synthesis of a thiolate-based α-hydroxytropolone library with a dynamic bioactivity profile
Here we describe a rapid and divergent synthetic route toward structurally novel αHTs functionalized with either one or two thioether or sulfonyl appendages. Evaluation of this library against hepatitis B and herpes simplex virus, as well as the pathogenic fungus Cryptococcus neoformans, revealed co...
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| Gepubliceerd in: | RSC Adv |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Royal Society of Chemistry
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7543996/ https://ncbi.nlm.nih.gov/pubmed/33042521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ra06383h |
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