Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the leading cause of primary liver cancers. Surveillance of individuals at specific risk of developing HCC, early diagnostic markers, and new therapeutic approaches are essential to obtain a reduction in disease-related mortality. Apurinic/apyrimidinic e...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Bazzani, Veronica, Barchiesi, Arianna, Radecka, Dorota, Pravisani, Riccardo, Guadagno, Antonio, Di Loreto, Carla, Baccarani, Umberto, Vascotto, Carlo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542375/
https://ncbi.nlm.nih.gov/pubmed/33028238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07258-6
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