Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the leading cause of primary liver cancers. Surveillance of individuals at specific risk of developing HCC, early diagnostic markers, and new therapeutic approaches are essential to obtain a reduction in disease-related mortality. Apurinic/apyrimidinic e...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Bazzani, Veronica, Barchiesi, Arianna, Radecka, Dorota, Pravisani, Riccardo, Guadagno, Antonio, Di Loreto, Carla, Baccarani, Umberto, Vascotto, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542375/
https://ncbi.nlm.nih.gov/pubmed/33028238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07258-6
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