Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the leading cause of primary liver cancers. Surveillance of individuals at specific risk of developing HCC, early diagnostic markers, and new therapeutic approaches are essential to obtain a reduction in disease-related mortality. Apurinic/apyrimidinic e...

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Publicat a:BMC Cancer
Autors principals: Bazzani, Veronica, Barchiesi, Arianna, Radecka, Dorota, Pravisani, Riccardo, Guadagno, Antonio, Di Loreto, Carla, Baccarani, Umberto, Vascotto, Carlo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542375/
https://ncbi.nlm.nih.gov/pubmed/33028238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07258-6
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