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Wnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis

Skeletal muscle and the neuromuscular junction are the earliest sites to manifest pathological changes in amyotrophic lateral sclerosis (ALS). Based on prior studies, we have identified a molecular signature in muscle that develops early in ALS and parallels disease progression. This signature repre...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Kwan, Thaddaeus, Kazamel, Mohamed, Thoenes, Kristina, Si, Ying, Jiang, Nan, King, Peter H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541525/
https://ncbi.nlm.nih.gov/pubmed/33028902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73845-z
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