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Muscle MicroRNA Signatures as Biomarkers of Disease Progression in Amyotrophic Lateral Sclerosis

ALS is a fatal neurodegenerative disorder of motor neurons leading to progressive atrophy and weakness of muscles. Some of the earliest pathophysiological changes occur at the level of skeletal muscle and the neuromuscular junction. We previously identified distinct mRNA patterns, including members...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Si, Ying, Cui, Xianqin, Crossman, David K., Hao, Jiaying, Kazamel, Mohamed, Kwon, Yuri, King, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891369/
https://ncbi.nlm.nih.gov/pubmed/29486297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.02.009
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