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Wnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis

Skeletal muscle and the neuromuscular junction are the earliest sites to manifest pathological changes in amyotrophic lateral sclerosis (ALS). Based on prior studies, we have identified a molecular signature in muscle that develops early in ALS and parallels disease progression. This signature repre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kwan, Thaddaeus, Kazamel, Mohamed, Thoenes, Kristina, Si, Ying, Jiang, Nan, King, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541525/
https://ncbi.nlm.nih.gov/pubmed/33028902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73845-z
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