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Wnt and Extraocular Muscle Sparing in Amyotrophic Lateral Sclerosis

PURPOSE. The extraocular muscles (EOM) and their motor neurons are spared in amyotrophic lateral sclerosis (ALS). In limb muscle, axon retraction from the neuromuscular junctions occurs early in the disease. Wnts, a conserved family of secreted signaling molecules, play a critical role in neuromuscu...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: McLoon, Linda K., Harandi, Vahid M., Brännström, Thomas, Andersen, Peter M., Liu, Jing-Xia
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580151/
https://ncbi.nlm.nih.gov/pubmed/25125606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14886
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