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Wnt and Extraocular Muscle Sparing in Amyotrophic Lateral Sclerosis

PURPOSE. The extraocular muscles (EOM) and their motor neurons are spared in amyotrophic lateral sclerosis (ALS). In limb muscle, axon retraction from the neuromuscular junctions occurs early in the disease. Wnts, a conserved family of secreted signaling molecules, play a critical role in neuromuscu...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: McLoon, Linda K., Harandi, Vahid M., Brännström, Thomas, Andersen, Peter M., Liu, Jing-Xia
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580151/
https://ncbi.nlm.nih.gov/pubmed/25125606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14886
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