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Wnt and Extraocular Muscle Sparing in Amyotrophic Lateral Sclerosis
PURPOSE. The extraocular muscles (EOM) and their motor neurons are spared in amyotrophic lateral sclerosis (ALS). In limb muscle, axon retraction from the neuromuscular junctions occurs early in the disease. Wnts, a conserved family of secreted signaling molecules, play a critical role in neuromuscu...
Gespeichert in:
| Veröffentlicht in: | Invest Ophthalmol Vis Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Association for Research in Vision and Ophthalmology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580151/ https://ncbi.nlm.nih.gov/pubmed/25125606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14886 |
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