The long non-coding RNA NEAT1 promotes sarcoma metastasis by regulating RNA splicing pathways

Soft tissue sarcomas (STSs) are rare malignancies showing lineage differentiation toward diverse mesenchymal tissues. Half of all high-grade STSs develop lung metastasis with a median survival of 15 months. Here we use a genetically engineered mouse model (GEMM) that mimics undifferentiated pleomorp...

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Publicado en:Mol Cancer Res
Autores principales: Huang, Jianguo, Sachdeva, Mohit, Xu, Eric, Robinson, Timothy J., Luo, Lixia, Ma, Yan, Williams, Nerissa T., Lopez, Omar, Cervia, Lisa D., Yuan, Fan, Qin, Xiaodi, Zhang, Dadong, Owzar, Kouros, Gokgoz, Nalan, Seto, Andrew, Okada, Tomoyo, Singer, Samuel, Andrulis, Irene L., Wunder, Jay S., Lazar, Alexander J., Rubin, Brian P., Pipho, Krista, Mello, Stephano S, Giudice, Jimena, Kirsch, David G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541426/
https://ncbi.nlm.nih.gov/pubmed/32561656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-1170
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