The long non-coding RNA NEAT1 promotes sarcoma metastasis by regulating RNA splicing pathways

Soft tissue sarcomas (STSs) are rare malignancies showing lineage differentiation toward diverse mesenchymal tissues. Half of all high-grade STSs develop lung metastasis with a median survival of 15 months. Here we use a genetically engineered mouse model (GEMM) that mimics undifferentiated pleomorp...

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Publicado no:Mol Cancer Res
Main Authors: Huang, Jianguo, Sachdeva, Mohit, Xu, Eric, Robinson, Timothy J., Luo, Lixia, Ma, Yan, Williams, Nerissa T., Lopez, Omar, Cervia, Lisa D., Yuan, Fan, Qin, Xiaodi, Zhang, Dadong, Owzar, Kouros, Gokgoz, Nalan, Seto, Andrew, Okada, Tomoyo, Singer, Samuel, Andrulis, Irene L., Wunder, Jay S., Lazar, Alexander J., Rubin, Brian P., Pipho, Krista, Mello, Stephano S, Giudice, Jimena, Kirsch, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541426/
https://ncbi.nlm.nih.gov/pubmed/32561656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-1170
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