Antibody escape by polyomavirus capsid mutation facilitates neurovirulence

JCPyV polyomavirus, a member of the human virome, causes progressive multifocal leukoencephalopathy (PML), an oft-fatal demyelinating brain disease in individuals receiving immunomodulatory therapies. Mutations in the major viral capsid protein, VP1, are common in JCPyV from PML patients (JCPyV-PML)...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Lauver, Matthew D, Goetschius, Daniel J, Netherby-Winslow, Colleen S, Ayers, Katelyn N, Jin, Ge, Haas, Daniel G, Frost, Elizabeth L, Cho, Sung Hyun, Bator, Carol M, Bywaters, Stephanie M, Christensen, Neil D, Hafenstein, Susan L, Lukacher, Aron E
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Immunology and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541085/
https://ncbi.nlm.nih.gov/pubmed/32940605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61056
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki