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Antibody escape by polyomavirus capsid mutation facilitates neurovirulence
JCPyV polyomavirus, a member of the human virome, causes progressive multifocal leukoencephalopathy (PML), an oft-fatal demyelinating brain disease in individuals receiving immunomodulatory therapies. Mutations in the major viral capsid protein, VP1, are common in JCPyV from PML patients (JCPyV-PML)...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541085/ https://ncbi.nlm.nih.gov/pubmed/32940605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61056 |
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