High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility

Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. HPV is epitheliotropic and its replication is tightly associated with terminal keratinocyte differentiation making production and purification of high titer virus preparations for research problemat...

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Vydáno v:Sci Rep
Hlavní autoři: Goetschius, Daniel J., Hartmann, Samantha R., Subramanian, Suriyasri, Bator, Carol M., Christensen, Neil D., Hafenstein, Susan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876116/
https://ncbi.nlm.nih.gov/pubmed/33568731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83076-5
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