CD8 T Cells and STAT1 Signaling Are Essential Codeterminants in Protection from Polyomavirus Encephalopathy

JC polyomavirus (JCPyV), a human-specific virus, causes the aggressive brain-demyelinating disease progressive multifocal leukoencephalopathy (PML) in individuals with depressed immune status. The increasing incidence of PML in patients receiving immunotherapeutic and chemotherapeutic agents creates...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mockus, Taryn E., Netherby-Winslow, Colleen S., Atkins, Hannah M., Lauver, Matthew D., Jin, Ge, Ren, Heather M., Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108847/
https://ncbi.nlm.nih.gov/pubmed/31996425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02038-19
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