PD-1 Dynamically Regulates Inflammation and Development of Brain-Resident Memory CD8 T Cells During Persistent Viral Encephalitis

Programmed cell death-1 (PD-1) receptor signaling dampens the functionality of T cells faced with repetitive antigenic stimulation from chronic infections or tumors. Using intracerebral (i.c.) inoculation with mouse polyomavirus (MuPyV), we have shown that CD8 T cells establish a PD-1(hi), tissue-re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shwetank, Frost, Elizabeth L., Mockus, Taryn E., Ren, Heather M., Toprak, Mesut, Lauver, Matthew D., Netherby-Winslow, Colleen S., Jin, Ge, Cosby, Jennifer M., Evavold, Brian D., Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499176/
https://ncbi.nlm.nih.gov/pubmed/31105690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00783
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados