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Biophysical studies of HIV-1 glycoprotein-41 interactions with peptides and small molecules – Effect of lipids and detergents
BACKGROUND: The hydrophobic pocket (HP) of HIV-1 glycoprotein-41 ectodomain is defined by two chains of the N-heptad repeat trimer, within the protein-protein interface that mediates 6HB formation. It is a potential target for inhibitors of viral fusion, but its hydrophobic nature and proximity to m...
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| Publicado no: | Biochim Biophys Acta Gen Subj |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7540966/ https://ncbi.nlm.nih.gov/pubmed/32889078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129724 |
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