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Design and characterization of swapped-domain constructs of HIV-1 glycoprotein-41 as receptors for drug discovery
Four new swapped-domain constructs of the ectodomain of human immunodeficiency virus type 1 glycoprotein-41 (gp41) were prepared. The gp41 ectodomain consists of 50-residue N-heptad repeat (NHR), 36-residue disulfide-bonded loop and 39-residue C-heptad repeat (CHR). It folds into a hairpin structure...
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Publicado no: | Protein Eng Des Sel |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366113/ https://ncbi.nlm.nih.gov/pubmed/25792539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzv006 |
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