A single mutation (V64G) within the RING Domain of Z attenuates Junin virus

Junin virus (JUNV) is a New World arenavirus that is the causative agent of Argentine hemorrhagic fever (AHF). Candid#1 (Can) is a live-attenuated vaccine strain of JUNV that since its introduction has resulted in a marked decrease in AHF incidence within the endemic regions of the Pampas in Argenti...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Hallam, Steven J., Manning, John T., Maruyama, Junki, Seregin, Alexey, Huang, Cheng, Walker, David H., de la Torre, Juan Carlos, Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540883/
https://ncbi.nlm.nih.gov/pubmed/32976538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008555
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