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Systematic Evaluation of Imine‐Reducing Enzymes: Common Principles in Imine Reductases, β‐Hydroxy Acid Dehydrogenases, and Short‐Chain Dehydrogenases/ Reductases

The enzymatic, asymmetric reduction of imines is catalyzed by imine reductases (IREDs), members of the short‐chain dehydrogenase/reductase (SDR) family, and β‐hydroxy acid dehydrogenase (βHAD) variants. Systematic evaluation of the structures and substrate‐binding sites of the three enzyme families...

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Bibliografski detalji
Izdano u:Chembiochem
Glavni autori: Stockinger, Peter, Roth, Sebastian, Müller, Michael, Pleiss, Jürgen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540600/
https://ncbi.nlm.nih.gov/pubmed/32311225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000213
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