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Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism

Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first step, oxidation of retinol to retinaldehyde, is catalyzed by cytosolic alcohol dehydrogenases (ADHs) of the medium-chain dehydrogenase/reductase (MDR) superfamily and microsomal retinol dehydrogenases (...

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Detalhes bibliográficos
Main Authors: Parés, X., Farrés, J., Kedishvili, N., Duester, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654207/
https://ncbi.nlm.nih.gov/pubmed/19011747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8591-3
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