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Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism

Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first step, oxidation of retinol to retinaldehyde, is catalyzed by cytosolic alcohol dehydrogenases (ADHs) of the medium-chain dehydrogenase/reductase (MDR) superfamily and microsomal retinol dehydrogenases (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Parés, X., Farrés, J., Kedishvili, N., Duester, G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654207/
https://ncbi.nlm.nih.gov/pubmed/19011747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8591-3
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