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Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism
Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first step, oxidation of retinol to retinaldehyde, is catalyzed by cytosolic alcohol dehydrogenases (ADHs) of the medium-chain dehydrogenase/reductase (MDR) superfamily and microsomal retinol dehydrogenases (...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654207/ https://ncbi.nlm.nih.gov/pubmed/19011747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8591-3 |
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