Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids

Retinoic acid biosynthesis in vertebrates occurs in two consecutive steps: the oxidation of retinol to retinaldehyde followed by the oxidation of retinaldehyde to retinoic acid. Enzymes of the MDR (medium-chain dehydrogenase/reductase), SDR (short-chain dehydrogenase/reductase) and AKR (aldo-keto re...

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Detalhes bibliográficos
Main Authors: Gallego, Oriol, Belyaeva, Olga V., Porté, Sergio, Ruiz, F. Xavier, Stetsenko, Anton V., Shabrova, Elena V., Kostereva, Natalia V., Farrés, Jaume, Parés, Xavier, Kedishvili, Natalia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570161/
https://ncbi.nlm.nih.gov/pubmed/16787387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051988
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