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A Phase 2, Double‐Blind, Placebo‐Controlled Trial to Investigate Potential Drug‐Drug Interactions Between Cannabidiol and Clobazam

We investigated the effects of cannabidiol (CBD; 21‐day maintenance dose) on the pharmacokinetics (PK) of clobazam (CLB) and monitored the safety of CBD (or placebo) plus CLB in 20 patients with uncontrolled epilepsy on stable doses of CLB. Blood samples collected until 24 hours postdose were evalua...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: VanLandingham, Kevan E., Crockett, Julie, Taylor, Lesley, Morrison, Gilmour
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540496/
https://ncbi.nlm.nih.gov/pubmed/32652616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1634
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