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A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

BACKGROUND: A formal single ascending and multiple dose pharmacokinetic (PK) trial of cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD, the maximum tolerated dose, and to examine the effect of food on CBD PK parameters. OBJECTIVE: This trial assessed the s...

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Pubblicato in:CNS Drugs
Autori principali: Taylor, Lesley, Gidal, Barry, Blakey, Graham, Tayo, Bola, Morrison, Gilmour
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223703/
https://ncbi.nlm.nih.gov/pubmed/30374683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-018-0578-5
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