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A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

BACKGROUND: A formal single ascending and multiple dose pharmacokinetic (PK) trial of cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD, the maximum tolerated dose, and to examine the effect of food on CBD PK parameters. OBJECTIVE: This trial assessed the s...

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Publicado en:CNS Drugs
Main Authors: Taylor, Lesley, Gidal, Barry, Blakey, Graham, Tayo, Bola, Morrison, Gilmour
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223703/
https://ncbi.nlm.nih.gov/pubmed/30374683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-018-0578-5
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