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A Phase 1, Open‐Label, Parallel‐Group, Single‐Dose Trial of the Pharmacokinetics and Safety of Cannabidiol (CBD) in Subjects With Mild to Severe Hepatic Impairment

The pharmacokinetics and safety of a single oral dose of 200‐mg plant‐derived pharmaceutical formulation of highly purified cannabidiol (CBD) in oral solution (Epidiolex in the United States; 100 mg/mL) were assessed in subjects with mild to severe hepatic impairment (n =  8 each for mild and modera...

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Опубликовано в: :J Clin Pharmacol
Главные авторы: Taylor, Lesley, Crockett, Julie, Tayo, Bola, Morrison, Gilmour
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618279/
https://ncbi.nlm.nih.gov/pubmed/30921490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1412
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