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E35 ablates acute leukemia stem and progenitor cells in vitro and in vivo
Leukemia stem cells (LSCs) have critical functions in acute leukemia (AL) pathogenesis, participating in its initiation and relapse. Thus, identifying new molecules to eradicate LSCs represents a high priority for AL management. This work identified E35, a novel Emodin derivative, which strongly inh...
Gardado en:
| Publicado en: | J Cell Physiol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7540425/ https://ncbi.nlm.nih.gov/pubmed/31960417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29457 |
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