Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells

BACKGROUND: The poor outcomes for patients diagnosed with acute myeloid leukemia (AML) are largely attributed to leukemia stem cells (LSCs) which are difficult to eliminate with conventional therapy and responsible for relapse. Thus, new therapeutic strategies which could selectively target LSCs in...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Ding, Yahui, Gao, Huier, Zhang, Yu, Li, Ye, Vasdev, Neil, Gao, Yingdai, Chen, Yue, Zhang, Quan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034521/
https://ncbi.nlm.nih.gov/pubmed/27658462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0327-5
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