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Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells

BACKGROUND: The poor outcomes for patients diagnosed with acute myeloid leukemia (AML) are largely attributed to leukemia stem cells (LSCs) which are difficult to eliminate with conventional therapy and responsible for relapse. Thus, new therapeutic strategies which could selectively target LSCs in...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Ding, Yahui, Gao, Huier, Zhang, Yu, Li, Ye, Vasdev, Neil, Gao, Yingdai, Chen, Yue, Zhang, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034521/
https://ncbi.nlm.nih.gov/pubmed/27658462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0327-5
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