E35 ablates acute leukemia stem and progenitor cells in vitro and in vivo

Leukemia stem cells (LSCs) have critical functions in acute leukemia (AL) pathogenesis, participating in its initiation and relapse. Thus, identifying new molecules to eradicate LSCs represents a high priority for AL management. This work identified E35, a novel Emodin derivative, which strongly inh...

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Dettagli Bibliografici
Pubblicato in:J Cell Physiol
Autori principali: Chen, Yingyu, Zheng, Jing, Gan, Donghui, Chen, Yanxin, Zhang, Na, Chen, Yuwen, Lin, Zhenxing, Wang, Wenfeng, Chen, Haijun, Lin, Donghong, Hu, Jianda
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Original Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540425/
https://ncbi.nlm.nih.gov/pubmed/31960417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29457
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