Neuropathy symptom and change: Inotersen treatment of hereditary transthyretin amyloidosis

INTRODUCTION: Hereditary transthyretin‐mediated amyloidosis (hATTR) manifests as multisystem dysfunction, including progressive polyneuropathy. Inotersen, an antisense oligonucleotide, improved the course of neuropathic impairment in patients with hATTR in the pivotal NEURO‐TTR study (NCT01737398)....

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Publicado en:Muscle Nerve
Autores principales: Dyck, P. James B., Coelho, Teresa, Waddington Cruz, Marcia, Brannagan, Thomas H., Khella, Sami, Karam, Chafic, Berk, John L., Polydefkis, Michael J., Kincaid, John C., Wiesman, Janice F., Litchy, William J., Mauermann, Michelle L., Ackermann, Elizabeth J., Baker, Brenda F., Jung, Shiangtung W., Guthrie, Spencer, Pollock, Michael, Dyck, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Clinical Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540369/
https://ncbi.nlm.nih.gov/pubmed/32654156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.27023
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