mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin‐mediated amyloidosis

INTRODUCTION: Inotersen, an antisense oligonucleotide inhibitor of transthyretin (TTR) protein production, demonstrated significant benefit versus placebo in the modified Neuropathy Impairment Score (NIS) +7 neurophysiologic tests (mNIS+7) in patients with hereditary TTR‐mediated amyloidosis (hATTR)...

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Publicado en:Muscle Nerve
Main Authors: Dyck, P. James B., Kincaid, John C., Wiesman, Janice F., Polydefkis, Michael, Litchy, William J., Mauermann, Michelle L., Ackermann, Elizabeth J., Guthrie, Spencer, Pollock, Michael, Jung, Shiangtung W., Baker, Brenda F., Dyck, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2020
Assuntos:
Clinical Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540053/
https://ncbi.nlm.nih.gov/pubmed/32654212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.27022
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