mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin‐mediated amyloidosis

INTRODUCTION: Inotersen, an antisense oligonucleotide inhibitor of transthyretin (TTR) protein production, demonstrated significant benefit versus placebo in the modified Neuropathy Impairment Score (NIS) +7 neurophysiologic tests (mNIS+7) in patients with hereditary TTR‐mediated amyloidosis (hATTR)...

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Bibliografiske detaljer
Udgivet i:Muscle Nerve
Main Authors: Dyck, P. James B., Kincaid, John C., Wiesman, Janice F., Polydefkis, Michael, Litchy, William J., Mauermann, Michelle L., Ackermann, Elizabeth J., Guthrie, Spencer, Pollock, Michael, Jung, Shiangtung W., Baker, Brenda F., Dyck, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Clinical Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540053/
https://ncbi.nlm.nih.gov/pubmed/32654212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.27022
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