mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin‐mediated amyloidosis

INTRODUCTION: Inotersen, an antisense oligonucleotide inhibitor of transthyretin (TTR) protein production, demonstrated significant benefit versus placebo in the modified Neuropathy Impairment Score (NIS) +7 neurophysiologic tests (mNIS+7) in patients with hereditary TTR‐mediated amyloidosis (hATTR)...

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Enregistré dans:
Détails bibliographiques
Publié dans:Muscle Nerve
Auteurs principaux: Dyck, P. James B., Kincaid, John C., Wiesman, Janice F., Polydefkis, Michael, Litchy, William J., Mauermann, Michelle L., Ackermann, Elizabeth J., Guthrie, Spencer, Pollock, Michael, Jung, Shiangtung W., Baker, Brenda F., Dyck, Peter J.
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2020
Sujets:
Clinical Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540053/
https://ncbi.nlm.nih.gov/pubmed/32654212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.27022
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