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IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion.

Non-small cell lung cancer (NSCLC) is the deadliest form of cancer worldwide, due in part to its proclivity to metastasize. Identifying novel drivers of invasion and metastasis holds therapeutic potential for the disease. We conducted a gain-of-function invasion screen, which identified two separate...

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書目詳細資料
發表在:Oncogene
Main Authors: Bajaj, Rakhee, Kundu, Samrat T., Grzeskowiak, Caitlin L., Fradette, Jared J., Scott, Kenneth L., Creighton, Chad J., Gibbons, Don L.
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539228/
https://ncbi.nlm.nih.gov/pubmed/32753652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01410-z
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