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The role of epithelial–mesenchymal transition programming in invasion and metastasis: a clinical perspective

Epithelial–mesenchymal transition (EMT) is involved in normal developmental cellular processes, but it may also be co-opted by a subset of cancer cells, to enable them to invade and form metastases at distant sites. Several gene transcription factors regulate EMT, including Snail1, Snail2, Zeb1, Zeb...

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Detalhes bibliográficos
Main Authors: Creighton, Chad J, Gibbons, Don L, Kurie, Jonathan M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754282/
https://ncbi.nlm.nih.gov/pubmed/23986650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S35171
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