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Pathways for nicotinic receptor desensitization

Nicotinic acetylcholine receptors (AChRs) are ligand-gated ion channels that generate transient currents by binding agonists and switching rapidly between closed- and open-channel conformations. Upon sustained exposure to ACh, the cell response diminishes slowly because of desensitization, a process...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Autor Principal: Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537344/
https://ncbi.nlm.nih.gov/pubmed/32910188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012639
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