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Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels
Nicotinic ACh receptor channels (AChRs) exposed to high concentrations of ACh adopt ‘desensitized’ conformations that have a high affinity for the transmitter and no measurable ion conductance. Single-channel currents elicited by 0.1 or 1 mmACh were recorded from human embryonic kidney (HEK) cells t...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290321/ https://ncbi.nlm.nih.gov/pubmed/12042345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.016022 |
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