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Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels

Nicotinic ACh receptor channels (AChRs) exposed to high concentrations of ACh adopt ‘desensitized’ conformations that have a high affinity for the transmitter and no measurable ion conductance. Single-channel currents elicited by 0.1 or 1 mmACh were recorded from human embryonic kidney (HEK) cells t...

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Autori principali: Elenes, Sergio, Auerbach, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290321/
https://ncbi.nlm.nih.gov/pubmed/12042345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.016022
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