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Desensitization of Mouse Nicotinic Acetylcholine Receptor Channels : A Two-Gate Mechanism

The rate constants of acetylcholine receptor channels (AChR) desensitization and recovery were estimated from the durations and frequencies of clusters of single-channel currents. Diliganded-open AChR desensitize much faster than either unliganded- or diliganded-closed AChR, which indicates that the...

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Autori principali: Auerbach, Anthony, Akk, Gustav
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525745/
https://ncbi.nlm.nih.gov/pubmed/9689026
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