eQTL Colocalization Analyses Identify NTN4 as a Candidate Breast Cancer Risk Gene

Breast cancer genome-wide association studies (GWASs) have identified 150 genomic risk regions containing more than 13,000 credible causal variants (CCVs). The CCVs are predominantly noncoding and enriched in regulatory elements. However, the genes underlying breast cancer risk associations are larg...

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Veröffentlicht in:Am J Hum Genet
Hauptverfasser: Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Shi, Wei, Hillman, Kristine M., Kaufmann, Susanne, Hussein, Nehal, Kar, Siddhartha, Lima, Luize G., Ham, Sunyoung, Möller, Andreas, Chenevix-Trench, Georgia, Edwards, Stacey L., French, Juliet D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536644/
https://ncbi.nlm.nih.gov/pubmed/32871102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.08.006
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