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Cooperative dynamics across distinct structural elements regulate PTP1B activity
Protein-tyrosine phosphatase 1B (PTP1B) is the canonical enzyme for investigating how distinct structural elements influence enzyme catalytic activity. Although it is recognized that dynamics are essential for PTP1B function, the data collected thus far have not resolved whether distinct elements ar...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7535920/ https://ncbi.nlm.nih.gov/pubmed/32737198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014652 |
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