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Cooperative dynamics across distinct structural elements regulate PTP1B activity

Protein-tyrosine phosphatase 1B (PTP1B) is the canonical enzyme for investigating how distinct structural elements influence enzyme catalytic activity. Although it is recognized that dynamics are essential for PTP1B function, the data collected thus far have not resolved whether distinct elements ar...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Torgeson, Kristiane R., Clarkson, Michael W., Kumar, Ganesan Senthil, Page, Rebecca, Peti, Wolfgang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535920/
https://ncbi.nlm.nih.gov/pubmed/32737198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014652
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